TMPRSS6 Antikörper (N-Term)
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- Target Alle TMPRSS6 Antikörper anzeigen
- TMPRSS6 (Transmembrane Protease, serine 6 (TMPRSS6))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TMPRSS6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- LLWYFLGYKA EVMVSQVYSG SLRVLNRHFS QDLTRRESSA FRSETAKAQK
- Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against TMPRSS6. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TMPRSS6
- Top Product
- Discover our top product TMPRSS6 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 811 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TMPRSS6 (Transmembrane Protease, serine 6 (TMPRSS6))
- Andere Bezeichnung
- TMPRSS6 (TMPRSS6 Produkte)
- Synonyme
- IRIDA antikoerper, 1300008A22Rik antikoerper, transmembrane protease, serine 6 antikoerper, transmembrane serine protease 6 antikoerper, Tmprss6 antikoerper, TMPRSS6 antikoerper
- Hintergrund
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TMPRSS6 is a serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. TMPRSS6 can also activate urokinase-type plasminogen activator with low efficiency. TMPRSS6 may play a specialized role in matrix remodeling processes in liver. TMPRSS6 is required to sense iron deficiency. Overexpression of TMPRSS6 suppresses activation of the HAMP promoter.The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver.
Alias Symbols: IRIDA
Protein Interaction Partner: LAMA1, FN1, COL1A1,
Protein Size: 811 - Molekulargewicht
- 90 kDa
- Gen-ID
- 164656
- NCBI Accession
- NM_153609, NP_705837
- UniProt
- Q8IU80
- Pathways
- Transition Metal Ion Homeostasis
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