TMPRSS6 Antikörper (N-Term)

Produktnummer ABIN1881891

Zitiert in 2+ Publikationen. Der Kaninchen Polyklonal anti-TMPRSS6 Antikörper (Klon RB39227) (ABIN1881891) detektiert spezifisch TMPRSS6 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für TMPRSS6 Antikörper (N-Term) (ABIN1881891)

Target: TMPRSS6 (Transmembrane Protease, serine 6 (TMPRSS6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMPRSS6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB39227

Produktdetails anti-TMPRSS6 Antikörper

Bindungsspezifität: AA 85-114, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TMPRSS6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-114 amino acids from the N-terminal region of human TMPRSS6.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-TMPRSS6 Antikörper (ABIN1881891)

Altamura, DAlessio, Selle, Muckenthaler: "A novel TMPRSS6 mutation that prevents protease auto-activation causes IRIDA." in: The Biochemical journal, Vol. 431, Issue 3, pp. 363-71, (2010) (PubMed).

Ucisik-Akkaya, Davis, Do, Morrison, Stemmer, Amadio, Dorak: "Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection." in: Molecular human reproduction, Vol. 16, Issue 10, pp. 770-7, (2010) (PubMed).

Details zu TMPRSS6

Target: TMPRSS6 (Transmembrane Protease, serine 6 (TMPRSS6))

Andere Bezeichnung: TMPRSS6

Hintergrund: The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver.

Molekulargewicht: 90000

NCBI Accession: NP_705837

UniProt: Q8IU80

Pathways: Transition Metal Ion Homeostasis