FBXO15 Antikörper (N-Term)

Produktnummer ABIN2785229

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FBXO15 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Hund, Meerschweinchen, Pferd, Schwein, Kaninchen und Rind (Kuh).

Kurzübersicht für FBXO15 Antikörper (N-Term) (ABIN2785229)

Target: FBXO15 (F-Box Protein 15 (FBXO15))

Reaktivität: Human, Ratte, Hund, Meerschweinchen, Pferd, Schwein, Kaninchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXO15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FBXO15 Antikörper

Bindungsspezifität: N-Term

Sequenz: QDKEAGYWKK EYITKQIASV KAALADILKP VNPYTGLPVK TKEALRIFGL

Homologie: Cow: 79%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FBXO15. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FBXO15

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 434 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FBXO15

Target: FBXO15 (F-Box Protein 15 (FBXO15))

Andere Bezeichnung: FBXO15

Hintergrund: FBXO15 is the substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.Members of the F-box protein family, such as FBXO15, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Alias Symbols: FBX15, MGC39671
Protein Interaction Partner: CRLS1, UBA7, UBC, ABCB1, SKP1,
Protein Size: 434

Molekulargewicht: 49 kDa

Gen-ID: 201456

NCBI Accession: NM_152676, NP_689889

UniProt: Q8NCQ5