TRAF3IP2 Antikörper (N-Term)
Kurzübersicht für TRAF3IP2 Antikörper (N-Term) (ABIN2785129)
Target
Alle TRAF3IP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Verwendungszweck
- TRAF3IP2 Antibody - N-terminal region
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Sequenz
- IPVEVDESEP YPSQLLKPIP EYSPEEESEP PAPNIRNMAP NSLSAPTMLH
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Homologie
- Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against TRAF3IP2. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TRAF3IP2
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52863-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))
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Andere Bezeichnung
- TRAF3IP2
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Hintergrund
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Background Information: This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.
Gene Name: TRAF3 interacting protein 2
Alternative Symbols: ACT1, CIKS, C6orf2, C6orf4, C6orf5, C6orf6, CANDF8, PSORS13
Protein Name: Adapter protein CIKS
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Molekulargewicht
- 65kDa
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Gen-ID
- 10758
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NCBI Accession
- NP_671733
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UniProt
- O43734
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Pathways
- Production of Molecular Mediator of Immune Response
Target
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