MRPL10 Antikörper (N-Term)

Produktnummer ABIN2785111

Der Kaninchen Polyklonal anti-MRPL10 Antikörper (ABIN2785111) detektiert spezifisch MRPL10 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Meerschweinchen, Kaninchen, Pferd und Schwein.

Kurzübersicht für MRPL10 Antikörper (N-Term) (ABIN2785111)

Target: MRPL10 (Mitochondrial Ribosomal Protein L10 (MRPL10))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Kaninchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRPL10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MRPL10 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: MRPL10 Antibody - N-terminal region

Sequenz: HRRVMHFQRQ KLMAVTEYIP PKPAIHPSCL PSPPSPPQEE IGLIRLLRRE

Homologie: Dog: 83%, Guinea Pig: 77%, Horse: 83%, Human: 100%, Mouse: 85%, Pig: 85%, Rabbit: 92%, Rat: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against MRPL10. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MRPL10

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52830-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu MRPL10

Target: MRPL10 (Mitochondrial Ribosomal Protein L10 (MRPL10))

Andere Bezeichnung: MRPL10

Hintergrund:

Background Information: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 5q. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 5q.

Gene Name: Mitochondrial ribosomal protein L10

Alternative Symbols: L10MT, MRPL8, RPML8, MRP-L8, MRP-L10

Protein Name: 39S ribosomal protein L10, mitochondrial

Molekulargewicht: 29kDa

Gen-ID: 124995

NCBI Accession: NP_660298

UniProt: Q7Z7H8