EXOC3 Antikörper (Middle Region)

Produktnummer ABIN2784880

Produktdetails anti-EXOC3 Antikörper

Target: EXOC3 (Exocyst Complex Component 3 (EXOC3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EXOC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: LERTVTTRIE GTQADTRESD KMWLVRHLEI IRKYVLDDLI VAKNLMVQCF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against EXOC3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EXOC3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 745 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EXOC3

Target: EXOC3 (Exocyst Complex Component 3 (EXOC3))

Andere Bezeichnung: EXOC3 (EXOC3 Produkte)

Hintergrund: EXOC3 is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
Alias Symbols: SEC6, SEC6L1, Sec6p
Protein Interaction Partner: UBC, INPP5K, PRPF19, KIAA0907, EGFR, EXOC4, BUB3, MLH1, EXOC8, EXOC2, EXOC6, EXOC5, APP, MYO5A, Poc1b, RALA, GRIN2B, DLG3,
Protein Size: 745

Molekulargewicht: 85 kDa

Gen-ID: 11336

NCBI Accession: NM_007277, NP_009208

UniProt: Q6P2E8

Pathways: Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis