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EXOC3 Antikörper (Middle Region)

Dieses Anti-EXOC3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von EXOC3 in WB und IHC. Geeignet für Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio) und Hund.
Produktnummer ABIN2784880

Kurzübersicht für EXOC3 Antikörper (Middle Region) (ABIN2784880)

Target

Alle EXOC3 Antikörper anzeigen
EXOC3 (Exocyst Complex Component 3 (EXOC3))

Reaktivität

  • 35
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Hund

Wirt

  • 36
  • 2
Kaninchen

Klonalität

  • 32
  • 6
Polyklonal

Konjugat

  • 21
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser EXOC3 Antikörper ist unkonjugiert

Applikation

  • 35
  • 13
  • 13
  • 11
  • 8
  • 8
  • 6
  • 4
  • 3
  • 3
  • 2
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 15
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Sequenz

    LERTVTTRIE GTQADTRESD KMWLVRHLEI IRKYVLDDLI VAKNLMVQCF

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

    Produktmerkmale

    This is a rabbit polyclonal antibody against EXOC3. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human EXOC3
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 745 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    EXOC3 (Exocyst Complex Component 3 (EXOC3))

    Andere Bezeichnung

    EXOC3

    Hintergrund

    EXOC3 is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
    Alias Symbols: SEC6, SEC6L1, Sec6p
    Protein Interaction Partner: UBC, INPP5K, PRPF19, KIAA0907, EGFR, EXOC4, BUB3, MLH1, EXOC8, EXOC2, EXOC6, EXOC5, APP, MYO5A, Poc1b, RALA, GRIN2B, DLG3,
    Protein Size: 745

    Molekulargewicht

    85 kDa

    Gen-ID

    11336

    NCBI Accession

    NM_007277, NP_009208

    UniProt

    Q6P2E8

    Pathways

    Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis
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