GRAP Antikörper (Middle Region)

Produktnummer ABIN2784825

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GRAP in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Hund, Pferd und Kaninchen.

Kurzübersicht für GRAP Antikörper (Middle Region) (ABIN2784825)

Target: GRAP (GRB2-Related Adaptor Protein (GRAP))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Hund, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GRAP Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: GRAP Antibody - middle region

Sequenz: KRQIFLRDEE PLLKSPGACF AQAQFDFSAQ DPSQLSFRRG DIIEVLERPD

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GRAP. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GRAP

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52210-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu GRAP

Target: GRAP (GRB2-Related Adaptor Protein (GRAP))

Andere Bezeichnung: GRAP

Hintergrund:

Background Information: This gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain.

Gene Name: GRB2-related adaptor protein

Alternative Symbols: DFNB114

Protein Name: GRB2-related adapter protein

Molekulargewicht: 25kDa

Gen-ID: 10750

NCBI Accession: NP_006604

UniProt: Q13588