GRAP Antikörper (AA 128-217)

Produktnummer ABIN7267510

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GRAP in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für GRAP Antikörper (AA 128-217) (ABIN7267510)

Target: GRAP (GRB2-Related Adaptor Protein (GRAP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GRAP Antikörper

Bindungsspezifität: AA 128-217

Verwendungszweck: GRAP Rabbit pAb

Sequenz: LNELVDFYRT TTIAKKRQIF LRDEEPLLKS PGACFAQAQF DFSAQDPSQL SFRRGDIIEV LERPDPHWWR GRSCGRVGFF PRSYVQPVHL

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 128-217 of human GRAP (NP_006604.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GRAP

Target: GRAP (GRB2-Related Adaptor Protein (GRAP))

Andere Bezeichnung: GRAP

Hintergrund: This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.,GRAP,Signal Transduction,G protein signaling,Signal Transduction,GRAP

Molekulargewicht: 25kDa

Gen-ID: 10750

UniProt: Q13588