PPIH Antikörper (Middle Region)
Kurzübersicht für PPIH Antikörper (Middle Region) (ABIN2784802)
Target
Alle PPIH Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- DFMIQGGDFV NGDGTGVASI YRGPFADENF KLRHSAPGLL SMANSGPSTN
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Homologie
- Cow: 100%, Dog: 100%, Goat: 90%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 90%
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Produktmerkmale
- This is a rabbit polyclonal antibody against PPIH. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PPIH
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 177 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PPIH (Peptidylprolyl Isomerase H (Cyclophilin H) (PPIH))
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Andere Bezeichnung
- PPIH
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Hintergrund
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The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome.
Alias Symbols: CYP-20, CYPH, MGC5016, SnuCyp-20, USA-CYP
Protein Interaction Partner: N4BP2L2, HUWE1, UBC, SOX2, METTL18, BAG2, PRPF4, VCAM1, ITGA4, FN1, PAXIP1, PCMT1, PRPF31, PPIH, PRPF3, NHP2L1, CUL3, Prpf8, MEPCE, USP15, SART3, USP4, PRPF18,
Protein Size: 177 -
Molekulargewicht
- 19 kDa
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Gen-ID
- 10465
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NCBI Accession
- NM_006347, NP_006338
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UniProt
- O43447
Target
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