EIF2B1 Antikörper (C-Term)

Produktnummer ABIN2784713

Produktdetails anti-EIF2B1 Antikörper

Target: EIF2B1 (Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Schwein, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF2B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: ADTLKVAQTG QDLKEEHPWV DYTAPSLITL LFTDLGVLTP SAVSDELIKL

Homologie: Cow: 79%, Dog: 79%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 79%, Rabbit: 79%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against EIF2B1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human EIF2B1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 305 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EIF2B1

Target: EIF2B1 (Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1))

Andere Bezeichnung: EIF2B1 (EIF2B1 Produkte)

Synonyme: DDBDRAFT_0219393 antikoerper, DDBDRAFT_0231375 antikoerper, DDB_0219393 antikoerper, DDB_0231375 antikoerper, 26kDa antikoerper, D5Ertd406e antikoerper, EIF2B antikoerper, EIF2BA antikoerper, eIF-2a antikoerper, translation initiation factor eIF-2B alpha subunit antikoerper, hypothetical protein antikoerper, Translation initiation factor eIF-2B subunit alpha antikoerper, eukaryotic translation initiation factor 2B subunit alpha antikoerper, eukaryotic translation initiation factor 2B, subunit 1 (alpha) antikoerper, eIF2b1 antikoerper, PGTG_05021 antikoerper, ei2ba antikoerper, eif2b1 antikoerper, Eif2b1 antikoerper, EIF2B1 antikoerper

Hintergrund: EIF2B1 belongs to the EIF-2B alpha/beta/delta subunits family. It catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Defects in EIF2B1 are a cause of leukoencephalopathy with vanishing white matter (VWM).
Alias Symbols: EIF-2B, EIF-2Balpha, EIF2B, EIF2BA, MGC117409, MGC125868, MGC125869
Protein Interaction Partner: RD3, WDYHV1, GORASP2, EIF2B1, UBC, GCD2, GCD6, EIF2B2, STK11, DCC, MRPL4, EIF2S2, EIF2S1, ARL4D, CREBBP, ADRB2, ADRA2B, ADRA2C, ADRA2A, EIF2B5, DCD, PDIA4, EIF2B3, HNRNPL, ARHGDIA,
Protein Size: 305

Molekulargewicht: 34 kDa

Gen-ID: 1967

NCBI Accession: NM_001414, NP_001405

UniProt: Q14232

Pathways: Methionine Biosynthetic Process