Adrenomedullin Antikörper (C-Term)

Produktnummer ABIN2784687

Der Kaninchen Polyklonal anti-Adrenomedullin Antikörper (ABIN2784687) detektiert spezifisch Adrenomedullin in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Kaninchen.

Kurzübersicht für Adrenomedullin Antikörper (C-Term) (ABIN2784687)

Target: Adrenomedullin (ADM)

Reaktivität: Human, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adrenomedullin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Adrenomedullin Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: ADM Antibody - C-terminal region

Sequenz: VAPRSKISPQ GYGRRRRRSL PEAGPGRTLV SSKPQAHGAP APPSGSAPHF

Homologie: Human: 100%, Rabbit: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against ADM. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51920-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Adrenomedullin

Target: Adrenomedullin (ADM)

Andere Bezeichnung: ADM

Substanzklasse: Hormone

Hintergrund:

Background Information: Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element.

Gene Name: Adrenomedullin

Alternative Symbols: AM, PAMP

Protein Name: ADM

Molekulargewicht: 20kDa

Gen-ID: 133

NCBI Accession: NP_001115

UniProt: P35318

Pathways: Hormone Transport, Hormone Activity, C21-Steroid Hormone Metabolic Process, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation