ADH5 Antikörper (Middle Region)

Produktnummer ABIN2784616

Der Kaninchen Polyklonal Anti-ADH5-Antikörper wurde für WB validiert. Er ist geeignet, ADH5 in Proben von Human, Maus, Ratte, Schwein, Pferd und Kaninchen zu detektieren.

Kurzübersicht für ADH5 Antikörper (Middle Region) (ABIN2784616)

Target: ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))

Reaktivität: Human, Maus, Ratte, Schwein, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADH5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ADH5 Antikörper

Bindungsspezifität: Middle Region

Sequenz: KSVESVPKLV SEYMSKKIKV DEFVTHNLSF DEINKAFELM HSGKSIRTVV

Homologie: Horse: 79%, Human: 100%, Mouse: 93%, Pig: 79%, Rabbit: 83%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against ADH5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ADH5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 374 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ADH5

Target: ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))

Andere Bezeichnung: ADH5

Hintergrund: This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.
Alias Symbols: ADH-3, ADHX, FDH, FALDH, GSNOR, GSH-FDH
Protein Interaction Partner: UBC, HDAC1, SNTA1, ADH5, PQLC1, VTN, PRDX1, ESRRA, CSNK2B, ARNT, APP, TP63, TP73, TP53, CHD3,
Protein Size: 374

Molekulargewicht: 40 kDa

Gen-ID: 128

NCBI Accession: NM_000671, NP_000662

UniProt: P11766