ABAT Antikörper (Middle Region)
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- Target Alle ABAT Antikörper anzeigen
- ABAT (4-Aminobutyrate Aminotransferase (ABAT))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Ziege, Meerschweinchen, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ABAT Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- YRSKERGQRG FSQEELETCM INQAPGCPDY SILSFMGAFH GRTMGCLATT
- Homologie
- Cow: 93%, Dog: 86%, Goat: 77%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against ABAT. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ABAT
- Top Product
- Discover our top product ABAT Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 500 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ABAT (4-Aminobutyrate Aminotransferase (ABAT))
- Andere Bezeichnung
- ABAT (ABAT Produkte)
- Synonyme
- cb880 antikoerper, fj82a01 antikoerper, wu:fj82a01 antikoerper, BA0325 antikoerper, PSPTO0259 antikoerper, PSPTO0301 antikoerper, PSPTO1890 antikoerper, GABA-AT antikoerper, GABAT antikoerper, NPD009 antikoerper, GABA-T antikoerper, L-AIBAT antikoerper, 9630038C02Rik antikoerper, AI255750 antikoerper, ENSMUSG00000051226 antikoerper, Gabaat antikoerper, Gabat antikoerper, Gm9851 antikoerper, I54 antikoerper, Laibat antikoerper, X61497 antikoerper, beta-AlaAT antikoerper, 4-aminobutyrate aminotransferase antikoerper, 4-aminobutyrate--2-oxoglutarate transaminase antikoerper, GABA aminotransferase PLP-dependent PuuE antikoerper, 4-aminobutyrate aminotransferase, mitochondrial antikoerper, aspartate aminotransferase family protein antikoerper, 4-aminobutyrate aminotransferase S homeolog antikoerper, ABAT antikoerper, abat antikoerper, gabT antikoerper, puuE antikoerper, gabT-1 antikoerper, gabT-2 antikoerper, gabT-3 antikoerper, CNE01830 antikoerper, Mmwyl1_0047 antikoerper, CpipJ_CPIJ008729 antikoerper, KCR_RS04555 antikoerper, Bcenmc03_4909 antikoerper, Hden_0972 antikoerper, Dbac_2000 antikoerper, Mesil_2400 antikoerper, Trad_0121 antikoerper, abat.S antikoerper, Abat antikoerper
- Hintergrund
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4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95 % similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
Alias Symbols: GABA-AT, GABAT, NPD009
Protein Interaction Partner: LGR4, BAG3, ALDH5A1, ABAT,
Protein Size: 500 - Molekulargewicht
- 56 kDa
- Gen-ID
- 18
- NCBI Accession
- NM_020686, NP_065737
- UniProt
- P80404
- Pathways
- Monocarboxylic Acid Catabolic Process
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