DCLRE1C Antikörper (N-Term)

Produktnummer ABIN2784440

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DCLRE1C in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Meerschweinchen, Pferd, Rind (Kuh), Kaninchen, Hund und Zebrafisch (Danio rerio).

Kurzübersicht für DCLRE1C Antikörper (N-Term) (ABIN2784440)

Target: DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Rind (Kuh), Kaninchen, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DCLRE1C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DCLRE1C Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: DCLRE1C Antibody - N-terminal region

Sequenz: SSFEGQMAEY PTISIDRFDR ENLRARAYFL SHCHKDHMKG LRAPTLKRRL

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against DCLRE1C. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DCLRE1C

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51164-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu DCLRE1C

Target: DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

Andere Bezeichnung: DCLRE1C

Hintergrund:

Background Information: DCLRE1C is a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity, it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA).This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity, it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA).

Gene Name: DNA cross-link repair 1C

Alternative Symbols: SCIDA, SNM1C, A-SCID, RS-SCID, DCLREC1C

Protein Name: Protein artemis

Molekulargewicht: 78kDa

Gen-ID: 64421

NCBI Accession: NP_001029027

UniProt: Q96SD1

Pathways: DNA Reparatur