URI1 Antikörper (Middle Region)

Produktnummer ABIN2784320

Der Kaninchen Polyklonal anti-URI1 Antikörper (ABIN2784320) detektiert spezifisch URI1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen und Meerschweinchen.

Kurzübersicht für URI1 Antikörper (Middle Region) (ABIN2784320)

Target: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser URI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-URI1 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: C19orf2 Antibody - middle region

Sequenz: NGEYVPRKSI LKSRSRENSV CSDTSESSAA EFDDRRGVLR SISCEEATCS

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 80%

Produktmerkmale: This is a rabbit polyclonal antibody against C19orf2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human C19orf2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50771-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu URI1

Target: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Andere Bezeichnung: C19orf2

Hintergrund:

Background Information: The function of the C19orf2 protein remains unknown.The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Name: URI1, prefoldin-like chaperone

Alternative Symbols: RMP, URI, NNX3, C19orf2, PPP1R19

Protein Name: Chromosome 19 open reading frame 2 EMBL AAH67259.1

Molekulargewicht: 55kDa

Gen-ID: 8725

NCBI Accession: NP_604431

UniProt: Q6NX55