URI1 Antikörper (Middle Region)

Produktnummer ABIN2784320

Dieses Anti-URI1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von URI1 in WB. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen und Meerschweinchen.

Kurzübersicht für URI1 Antikörper (Middle Region) (ABIN2784320)

Target: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser URI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-URI1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: NGEYVPRKSI LKSRSRENSV CSDTSESSAA EFDDRRGVLR SISCEEATCS

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 80%

Produktmerkmale: This is a rabbit polyclonal antibody against C19orf2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human C19orf2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 495 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu URI1

Target: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Andere Bezeichnung: C19orf2

Hintergrund: The function of the C19orf2 protein remains unknown.The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: FLJ10575, NNX3, RMP, URI, C19orf2, PPP1R19
Protein Interaction Partner: RPAP3, UBC, ITCH, NEDD4, ATF7, TTI1, RUVBL1, RPS6KB1, PPP1CC, HSP90AA1, APP, UXT, RPAP2, GPN1, RUVBL2, STAP1, POLR2E, URI1, DMAP1, GTF2F2,
Protein Size: 495

Molekulargewicht: 55 kDa

Gen-ID: 8725

NCBI Accession: NM_134447, NP_604431

UniProt: Q6NX55