ING4 Antikörper (Middle Region)

Produktnummer ABIN2784250

Der Kaninchen Polyklonal anti-ING4 Antikörper wird verwendet zum Nachweis von ING4 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen und Pferd. Er wurde validiert für WB.

Kurzübersicht für ING4 Antikörper (Middle Region) (ABIN2784250)

Target: ING4 (Inhibitor of Growth Family, Member 4 (ING4))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ING4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ING4 Antikörper

Bindungsspezifität: Middle Region

Sequenz: DLKEKQIESS DYDSSSSKGK KSRTQKEKKA ARARSKGKNS DEEAPKTAQK

Homologie: Cow: 100%, Dog: 87%, Guinea Pig: 87%, Horse: 87%, Human: 100%, Mouse: 100%, Rabbit: 87%, Rat: 87%

Produktmerkmale: This is a rabbit polyclonal antibody against ING4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ING4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 248 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ING4

Target: ING4 (Inhibitor of Growth Family, Member 4 (ING4))

Andere Bezeichnung: ING4

Hintergrund: ING4 is a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway.This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins.
Alias Symbols: MGC12557, my036, p29ING4
Protein Interaction Partner: NAV2, GADD45A, SUV39H1, RELA, CDC34, HIST3H3, MSX1, TP53, PADI4, ING4, KAT7, JADE1, UBC, HIST1H3A, TLX3, JADE2, HOXB9, Trp53, EGLN1, G3BP2, PPFIA1, UBE2D2, EP300, HHT2, HHT1, HIST2H3C, JADE3, MEAF6, CDKN2A,
Protein Size: 248

Molekulargewicht: 28 kDa

Gen-ID: 51147

NCBI Accession: NM_016162, NP_057246

UniProt: Q9UNL4