ING4 Antikörper (Middle Region)

Produktnummer ABIN2784250

Produktdetails anti-ING4 Antikörper

Target: ING4 (Inhibitor of Growth Family, Member 4 (ING4))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ING4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DLKEKQIESS DYDSSSSKGK KSRTQKEKKA ARARSKGKNS DEEAPKTAQK

Homologie: Cow: 100%, Dog: 87%, Guinea Pig: 87%, Horse: 87%, Human: 100%, Mouse: 100%, Rabbit: 87%, Rat: 87%

Produktmerkmale: This is a rabbit polyclonal antibody against ING4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ING4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 248 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ING4

Target: ING4 (Inhibitor of Growth Family, Member 4 (ING4))

Andere Bezeichnung: ING4 (ING4 Produkte)

Hintergrund: ING4 is a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway.This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins.
Alias Symbols: MGC12557, my036, p29ING4
Protein Interaction Partner: NAV2, GADD45A, SUV39H1, RELA, CDC34, HIST3H3, MSX1, TP53, PADI4, ING4, KAT7, JADE1, UBC, HIST1H3A, TLX3, JADE2, HOXB9, Trp53, EGLN1, G3BP2, PPFIA1, UBE2D2, EP300, HHT2, HHT1, HIST2H3C, JADE3, MEAF6, CDKN2A,
Protein Size: 248

Molekulargewicht: 28 kDa

Gen-ID: 51147

NCBI Accession: NM_016162, NP_057246

UniProt: Q9UNL4