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YAP1 Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch YAP1 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Schaf, Rind (Kuh), Pferd, Schwein und Kaninchen.
Produktnummer ABIN2784221

Kurzübersicht für YAP1 Antikörper (C-Term) (ABIN2784221)

Target

Alle YAP1 Antikörper anzeigen
YAP1 (Yes-Associated Protein 1 (YAP1))

Reaktivität

  • 145
  • 82
  • 59
  • 6
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Schaf, Rind (Kuh), Pferd, Schwein, Kaninchen

Wirt

  • 130
  • 17
  • 1
  • 1
  • 1
Kaninchen

Klonalität

  • 112
  • 35
  • 2
Polyklonal

Konjugat

  • 88
  • 8
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser YAP1 Antikörper ist unkonjugiert

Applikation

  • 112
  • 46
  • 37
  • 28
  • 27
  • 27
  • 23
  • 22
  • 13
  • 11
  • 7
  • 7
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 28
    • 15
    • 15
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequenz

    QLPTLEQDGG TQNPVSSPGM SQELRTMTTN SSDPFLNSGT YHSRDESTDS

    Homologie

    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against YAP1. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the C terminal region of human YAP1
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 504 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    YAP1 (Yes-Associated Protein 1 (YAP1))

    Andere Bezeichnung

    YAP1

    Hintergrund

    YAP1 is the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes proto-oncogene product. YAP1 contains a WW domain that is found in various structural, regulatory and signaling molecules in yeast, nematode, and mammals, and may be involved in protein-protein interaction.
    Alias Symbols: YAP, YAP2, YAP65, YKI
    Protein Interaction Partner: ABL1, TP73, RUNX1, AMOT, UBC, FBXW7, ARFIP1, RTF1, PAPOLA, PRMT3, TOM1, TSNAX, STAT1, MAP2K1, NF2, WBP2, RASSF8, YWHAQ, INADL, RAPGEF2, TJP2, SLC9A3R2, PDLIM7, LATS1, MPDZ, RAE1, ARID1A, YWHAZ, YWHAH, YWHAG, YWHAE, YWHAB, TP53BP2, TEAD3, TEAD1, SMARCD1, D
    Protein Size: 504

    Molekulargewicht

    54 kDa

    Gen-ID

    10413

    NCBI Accession

    NM_001130145, NP_001123617

    UniProt

    P46937

    Pathways

    MAPK Signalweg, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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