ING1 Antikörper (C-Term)

Produktnummer ABIN2784213

Der Kaninchen Polyklonal Anti-ING1-Antikörper wurde für WB validiert. Er ist geeignet, ING1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Zebrafisch (Danio rerio), Pferd und Kaninchen zu detektieren.

Kurzübersicht für ING1 Antikörper (C-Term) (ABIN2784213)

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Zebrafisch (Danio rerio), Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ING1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ING1 Antikörper

Bindungsspezifität: C-Term

Sequenz: EKKAKTSKKK KRSKAKAERE ASPADLPIDP NEPTYCLCNQ VSYGEMIGCD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against ING1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ING1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 279 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ING1

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Andere Bezeichnung: ING1

Hintergrund: ING1 is a tumor suppressor protein that can induce cell growth arrest and apoptosis. The protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of ING1 gene have been detected in various cancers.This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a
Protein Interaction Partner: SIRT1, SIRT2, UBC, HDAC1, KIAA0101, PCNA, RBP1, RBBP7, RBBP4, HDAC2, BRMS1L, SIN3A, BRMS1, SAP30, ELAVL1, SMURF1, COPS2, NQO1, HIST2H3C, MRGBP, YWHAZ, YWHAH, YWHAG, YWHAE, YWHAB, KPNA2, KPNB1, YWHAQ, SFN, ESR1, LMNA, CDKN2A, TP53, KAT2B, DMAP1, EP300, HHT
Protein Size: 279

Molekulargewicht: 32 kDa

Gen-ID: 3621

NCBI Accession: NM_198219, NP_937862

UniProt: Q5T9H0

Pathways: Protein targeting to Nucleus, Autophagie