FIP200 Antikörper (C-Term)

Produktnummer ABIN2784196

Dieser Anti-FIP200 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von FIP200 in WB und IHC. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Zebrafisch (Danio rerio).

Kurzübersicht für FIP200 Antikörper (C-Term) (ABIN2784196)

Target: FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FIP200 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-FIP200 Antikörper

Bindungsspezifität: C-Term

Sequenz: SGASRRPWVL GKVMEKEYCQ AKKAQNRFKV PLGTKFYRVK AVSWNKKV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RB1CC1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RB1CC1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1591 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FIP200

Target: FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))

Andere Bezeichnung: RB1CC1

Hintergrund: RB1CC1 is implicated in the regulation of RB1 expression. It functions as a DNA-binding transcription factor. RB1CC1 is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. The expression of RB1CC1 is, thus, a prerequisite for myogenic differentiation. RB1CC1 is frequently mutated in breast cancer and shows characteristics of a classical tumor suppressor gene.
Alias Symbols: CC1, DRAGOU14, FIP200
Protein Interaction Partner: ATG16L1, SESN2, ATG5, UBC, EXOC1, DYRK2, PINK1, CALCOCO2, RFWD2, CTNNB1, GABARAPL1, GABARAP, VHL, RNF111, SMARCB1, SKIL, SKI, TBKBP1, TP53, ATG13, ULK2, SAFB2, ULK1, SAFB, RPA2, RPA1, PRKAB2, PRKAA2, HSBP1, MAP1LC3C, SMCR8, ATG101, YLPM1, TBK1, RBMX, PTK2
Protein Size: 1591

Molekulargewicht: 183 kDa

Gen-ID: 9821

NCBI Accession: NM_001083617, NP_001077086

UniProt: Q8TDY2

Pathways: Regulation of Cell Size, Autophagie