HES5 Antikörper (Middle Region)

Produktnummer ABIN2784162

Produktdetails anti-HES5 Antikörper

Target: HES5 (Hairy and Enhancer of Split 5 (HES5))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HES5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AASDTQMKLL YHFQRPPAAP AAPAKEPKAP GAAPPPALSA KATAAAAAAH

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 85%, Human: 100%, Mouse: 88%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against HES5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HES5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 166 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HES5

Target: HES5 (Hairy and Enhancer of Split 5 (HES5))

Andere Bezeichnung: HES5 (HES5 Produkte)

Hintergrund: This gene encodes a member of a family of basic helix-loop-helix transcriptional repressors. The protein product of this gene, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of this gene have been associated with developmental diseases and cancer.
Alias Symbols: bHLHb38
Protein Interaction Partner: STAT3, JAK2, UBC,
Protein Size: 166

Molekulargewicht: 18 kDa

Gen-ID: 388585

NCBI Accession: NM_001010926, NP_001010926

UniProt: Q5TA89

Pathways: Stem Cell Maintenance, Tube Formation