JAM3 Antikörper (N-Term)
Kurzübersicht für JAM3 Antikörper (N-Term) (ABIN2784060)
Target
Alle JAM3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Verwendungszweck
- JAM3 Antibody - N-terminal region
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Sequenz
- SSNRTPVVQE FESVELSCII TDSQTSDPRI EWKKIQDEQT TYVFFDNKIQ
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Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against JAM3. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human JAM3
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50121-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- JAM3 (Junctional Adhesion Molecule 3 (JAM3))
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Andere Bezeichnung
- JAM3
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Hintergrund
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Background Information: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. JAM3, one member of the immunoglobulin superfamily, is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. JAM3 is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family.
Gene Name: Junctional adhesion molecule 3
Alternative Symbols: JAMC, JAM-2, JAM-3, JAM-C
Protein Name: Junctional adhesion molecule C
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Molekulargewicht
- 28kDa
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Gen-ID
- 83700
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UniProt
- Q9BX67
Target
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