JAM3 Antikörper (N-Term)

Produktnummer ABIN2784060

Produktdetails anti-JAM3 Antikörper

Target: JAM3 (Junctional Adhesion Molecule 3 (JAM3))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JAM3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SSNRTPVVQE FESVELSCII TDSQTSDPRI EWKKIQDEQT TYVFFDNKIQ

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against JAM3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human JAM3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 259 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu JAM3

Target: JAM3 (Junctional Adhesion Molecule 3 (JAM3))

Andere Bezeichnung: JAM3 (JAM3 Produkte)

Hintergrund: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. JAM3, one member of the immunoglobulin superfamily, is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. JAM3 is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family.
Alias Symbols: FLJ14529, JAM-C, JAMC
Protein Interaction Partner: JAM3, JAM2, UBC, PICK1, F2RL2, TJP1, ITGAX, ITGAM, PARD3,
Protein Size: 259

Molekulargewicht: 28 kDa

Gen-ID: 83700

UniProt: Q9BX67, B3KWG9