SPACA1 Antikörper (N-Term)

Produktnummer ABIN2783998

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SPACA1 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SPACA1 Antikörper (N-Term) (ABIN2783998)

Target: SPACA1 (Sperm Acrosome Associated 1 (SPACA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPACA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SPACA1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: SPACA1 Antibody - N-terminal region

Sequenz: TENNDSETAE NYAPPETEDV SNRNVVKEVE FGMCTVTCGI GVREVILTNG

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SPACA1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SPACA1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49984-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SPACA1

Target: SPACA1 (Sperm Acrosome Associated 1 (SPACA1))

Andere Bezeichnung: SPACA1

Hintergrund:

Background Information: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.

Gene Name: Sperm acrosome associated 1

Alternative Symbols: SAMP32

Protein Name: Sperm acrosome membrane-associated protein 1

Molekulargewicht: 32kDa

Gen-ID: 81833

NCBI Accession: NP_112222

UniProt: Q9HBV2