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LRRC8A Antikörper (N-Term)

LRRC8A Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2783752
  • Target Alle LRRC8A Antikörper anzeigen
    LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))
    Bindungsspezifität
    • 14
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 21
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)
    Wirt
    • 20
    • 1
    Kaninchen
    Klonalität
    • 20
    • 1
    Polyklonal
    Konjugat
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser LRRC8A Antikörper ist unkonjugiert
    Applikation
    • 21
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    IPVTELRYFA DTQPAYRILK PWWDVFTDYI SIVMLMIAVF GGTLQVTQDK
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against LRRC8A. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human LRRC8A
    Top Product
    Discover our top product LRRC8A Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 810 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))
    Andere Bezeichnung
    LRRC8A (LRRC8A Produkte)
    Synonyme
    AGM5 antikoerper, LRRC8 antikoerper, Lrrc8 antikoerper, mKIAA1437 antikoerper, wu:fb18g12 antikoerper, wu:fi21b10 antikoerper, LLRC8A antikoerper, leucine rich repeat containing 8 VRAC subunit A antikoerper, leucine rich repeat containing 8A antikoerper, leucine rich repeat containing 8 VRAC subunit Aa antikoerper, leucine-rich repeat containing 8 family member A S homeolog antikoerper, leucine rich repeat containing 8 family member A antikoerper, LRRC8A antikoerper, Lrrc8a antikoerper, lrrc8aa antikoerper, lrrc8a.S antikoerper
    Hintergrund
    LRRC8A is a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. LRRC8A is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
    Alias Symbols: FLJ10337, KIAA1437, LRRC8, AGM5
    Protein Interaction Partner: SDHA, ELAVL1, UBC,
    Protein Size: 810
    Molekulargewicht
    94 kDa
    Gen-ID
    56262
    NCBI Accession
    NM_019594, NP_062540
    UniProt
    Q8IWT6
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