LRRC8A Antikörper (C-Term)

Produktnummer ABIN1881512

Produktdetails anti-LRRC8A Antikörper

Target: LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))

Bindungsspezifität: AA 782-810, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRRC8A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LRRC8A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 782-810 amino acids from the C-terminal region of human LRRC8A.

Klon: RB30632

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-LRRC8A Antikörper (ABIN1881512)

Smits, Kajava: "LRRC8 extracellular domain is composed of 17 leucine-rich repeats." in: Molecular immunology, Vol. 41, Issue 5, pp. 561-2, (2004) (PubMed).

Conley: "Genes required for B cell development." in: The Journal of clinical investigation, Vol. 112, Issue 11, pp. 1636-8, (2003) (PubMed).

Details zu LRRC8A

Target: LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))

Andere Bezeichnung: LRRC8A (LRRC8A Produkte)

Synonyme: AGM5 antikoerper, LRRC8 antikoerper, Lrrc8 antikoerper, mKIAA1437 antikoerper, wu:fb18g12 antikoerper, wu:fi21b10 antikoerper, LLRC8A antikoerper, leucine rich repeat containing 8 VRAC subunit A antikoerper, leucine rich repeat containing 8A antikoerper, leucine rich repeat containing 8 VRAC subunit Aa antikoerper, leucine-rich repeat containing 8 family member A S homeolog antikoerper, leucine rich repeat containing 8 family member A antikoerper, LRRC8A antikoerper, Lrrc8a antikoerper, lrrc8aa antikoerper, lrrc8a.S antikoerper

Hintergrund: This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

Molekulargewicht: 94199

NCBI Accession: NP_001120716, NP_001120717, NP_062540

UniProt: Q8IWT6