ALG1 Antikörper (N-Term)

Produktnummer ABIN2783751

Der Kaninchen Polyklonal Anti-ALG1 Antikörper wurde für WB validiert. Er ist geeignet, ALG1 in Proben von Human, Maus, Ratte, Kaninchen, Rind (Kuh) und Saccharomyces cerevisiae zu detektieren.

Kurzübersicht für ALG1 Antikörper (N-Term) (ABIN2783751)

Target: ALG1 (Chitobiosyldiphosphodolichol beta-Mannosyltransferase (ALG1))

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ALG1 Antikörper

Bindungsspezifität: N-Term

Sequenz: VVLGDVGRSP RMQYHALSLA MHGFSVTLLG FCNSKPHDEL LQNNRIQIVG

Homologie: Cow: 79%, Human: 100%, Mouse: 85%, Rabbit: 79%, Rat: 79%, Yeast: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ALG1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ALG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 464 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ALG1

Target: ALG1 (Chitobiosyldiphosphodolichol beta-Mannosyltransferase (ALG1))

Andere Bezeichnung: ALG1

Hintergrund: ALG1 catalyzes the first mannosylation step in the biosynthesis of lipid-linked oligosaccharides. Defects in ALG1 are the cause of congenital disorder of glycosylation type 1K (CDG1K).The biosynthesis of lipid-linked oligosaccharides is highly conserved among eukaryotes and is catalyzed by 14 glycosyltransferases in an ordered stepwise manner. Mannosyltransferase I (MT I) catalyzes the first mannosylation step in this process.[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-421 BM767933.1 1-421 422-1179 AY359073.1 416-1173 1180-1444 CA455103.1 259-523 1445-1939 CD366777.1 17-511 c 1940-2122 BC031095.1 1931-2113 2123-2149 BQ002699.1 1-27 c
Alias Symbols: HMAT1, HMT-1, HMT1, MT-1, CDG1K, Mat-1, hMat-1
Protein Interaction Partner: UBC, FBXO6, BAG3, MMS19,
Protein Size: 464

Molekulargewicht: 52 kDa

Gen-ID: 56052

NCBI Accession: NM_019109, NP_061982

UniProt: Q9BT22