ALG1 Antikörper (C-Term)

Produktnummer ABIN2783688

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ALG1 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund und Meerschweinchen.Es wurde in 1 Publikation zitiert.

Kurzübersicht für ALG1 Antikörper (C-Term) (ABIN2783688)

Target: ALG1 (Chitobiosyldiphosphodolichol beta-Mannosyltransferase (ALG1))

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ALG1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: ALG1 Antibody - C-terminal region

Sequenz: VKHEENGLVF EDSEELAAQL QMLFSNFPDP AGKLNQFRKN LRESQQLRWD

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 92%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against ALG1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human ALG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49252-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ALG1 Antikörper (ABIN2783688)

Rind, Schmeiser, Thiel, Absmanner, Lübbehusen, Hocks, Apeshiotis, Wilichowski, Lehle, Körner: "A severe human metabolic disease caused by deficiency of the endoplasmatic mannosyltransferase hALG11 leads to congenital disorder of glycosylation-Ip." in: Human molecular genetics, Vol. 19, Issue 8, pp. 1413-24, (2010) (PubMed).

Details zu ALG1

Target: ALG1 (Chitobiosyldiphosphodolichol beta-Mannosyltransferase (ALG1))

Andere Bezeichnung: ALG1

Hintergrund:

Background Information: The enzyme encoded by this gene catalyzes the first mannosylation step in the biosynthesis of lipid-linked oligosaccharides. This gene is mutated in congenital disorder of glycosylation type Ik.

Gene Name: ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase

Alternative Symbols: HMT1, MT-1, CDG1K, HMAT1, HMT-1, Mat-1, hMat-1

Protein Name: chitobiosyldiphosphodolichol beta-mannosyltransferase

Molekulargewicht: 38kDa

Gen-ID: 56052

NCBI Accession: NP_061982

UniProt: B4DP08