UGT1A7 Antikörper (N-Term)

Produktnummer ABIN2783746

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch UGT1A7 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für UGT1A7 Antikörper (N-Term) (ABIN2783746)

Target: UGT1A7 (UDP Glucuronosyltransferase 1 Family, Polypeptide A7 (UGT1A7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UGT1A7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-UGT1A7 Antikörper

Bindungsspezifität: N-Term

Sequenz: VKTYSTSYTL EDQDREFMVF ADARWTAPLR SAFSLLTSSS NGIFDLFFSN

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against UGT1A7. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UGT1A7

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 530 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu UGT1A7

Target: UGT1A7 (UDP Glucuronosyltransferase 1 Family, Polypeptide A7 (UGT1A7))

Andere Bezeichnung: UGT1A7

Hintergrund: UGT1A7 is an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has moderate glucuronidase activity with phenols.This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has moderate glucuronidase activity with phenols. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: UDPGT, UGT1G, UGT-1G, UGT1.7, UGT1-07, UDPGT 1-7
Protein Size: 530

Molekulargewicht: 57 kDa

Gen-ID: 54577

NCBI Accession: NM_019077, NP_061950

UniProt: Q5DSZ7

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha