TMCO1 Antikörper (C-Term)

Produktnummer ABIN2783742

Der Kaninchen Polyklonal Anti-TMCO1-Antikörper wurde für WB validiert. Er ist geeignet, TMCO1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio) zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für TMCO1 Antikörper (C-Term) (ABIN2783742)

Target: TMCO1 (Transmembrane and Coiled-Coil Domains 1 (TMCO1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMCO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TMCO1 Antikörper

Bindungsspezifität: C-Term

Sequenz: CSFIFLYILC TMSIRQNIQK ILGLAPSRAA TKQAGGFLGP PPPSGKFS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against TMCO1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TMCO1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 188 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TMCO1 Antikörper (ABIN2783742)

Sharma, Burdon, Chidlow, Klebe, Crawford, Dimasi, Dave, Martin, Javadiyan, Wood, Casson, Danoy, Griggs, Hewitt, Landers, Mitchell, Mackey, Craig: "Association of genetic variants in the TMCO1 gene with clinical parameters related to glaucoma and characterization of the protein in the eye." in: Investigative ophthalmology & visual science, Vol. 53, Issue 8, pp. 4917-25, (2012) (PubMed).

Burdon, Macgregor, Hewitt, Sharma, Chidlow, Mills, Danoy, Casson, Viswanathan, Liu, Landers, Henders, Wood, Souzeau, Crawford, Leo, Wang, Rochtchina, Nyholt, Martin, Montgomery, Mitchell, Brown et al.: "Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1. ..." in: Nature genetics, Vol. 43, Issue 6, pp. 574-8, (2011) (PubMed).

Details zu TMCO1

Target: TMCO1 (Transmembrane and Coiled-Coil Domains 1 (TMCO1))

Andere Bezeichnung: TMCO1

Hintergrund: TMCO1 belongs to the TMCO1 family. The exact function of TMCO1 remains unknown.
Alias Symbols: HP10122, PCIA3, PNAS-136, RP11-466F5.7, TMCC4
Protein Interaction Partner: UBC, FBXO6, SERINC1, LAMTOR3, SRSF5, RPS10, ABCC1, ELAVL1, UNC93B1,
Protein Size: 188

Molekulargewicht: 21 kDa

Gen-ID: 54499

NCBI Accession: NM_019026, NP_061899

UniProt: Q9UM00