TMCO1 Antikörper (C-Term)

Produktnummer ABIN2783742

Es sind 2+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-TMCO1 Antikörper wird verwendet zum Nachweis von TMCO1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für TMCO1 Antikörper (C-Term) (ABIN2783742)

Target: TMCO1 (Transmembrane and Coiled-Coil Domains 1 (TMCO1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMCO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TMCO1 Antikörper

Bindungsspezifität: C-Term

Sequenz: CSFIFLYILC TMSIRQNIQK ILGLAPSRAA TKQAGGFLGP PPPSGKFS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against TMCO1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TMCO1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 188 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TMCO1 Antikörper (ABIN2783742)

Sharma, Burdon, Chidlow, Klebe, Crawford, Dimasi, Dave, Martin, Javadiyan, Wood, Casson, Danoy, Griggs, Hewitt, Landers, Mitchell, Mackey, Craig: "Association of genetic variants in the TMCO1 gene with clinical parameters related to glaucoma and characterization of the protein in the eye." in: Investigative ophthalmology & visual science, Vol. 53, Issue 8, pp. 4917-25, (2012) (PubMed).

Burdon, Macgregor, Hewitt, Sharma, Chidlow, Mills, Danoy, Casson, Viswanathan, Liu, Landers, Henders, Wood, Souzeau, Crawford, Leo, Wang, Rochtchina, Nyholt, Martin, Montgomery, Mitchell, Brown et al.: "Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1. ..." in: Nature genetics, Vol. 43, Issue 6, pp. 574-8, (2011) (PubMed).

Details zu TMCO1

Target: TMCO1 (Transmembrane and Coiled-Coil Domains 1 (TMCO1))

Andere Bezeichnung: TMCO1

Hintergrund: TMCO1 belongs to the TMCO1 family. The exact function of TMCO1 remains unknown.
Alias Symbols: HP10122, PCIA3, PNAS-136, RP11-466F5.7, TMCC4
Protein Interaction Partner: UBC, FBXO6, SERINC1, LAMTOR3, SRSF5, RPS10, ABCC1, ELAVL1, UNC93B1,
Protein Size: 188

Molekulargewicht: 21 kDa

Gen-ID: 54499

NCBI Accession: NM_019026, NP_061899

UniProt: Q9UM00