MAP3K2 Antikörper (N-Term)

Produktnummer ABIN2783679

Der Kaninchen Polyklonal Anti-MAP3K2-Antikörper wurde für WB validiert. Er ist geeignet, MAP3K2 in Proben von Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen, Schwein und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für MAP3K2 Antikörper (N-Term) (ABIN2783679)

Target: MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen, Schwein, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP3K2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAP3K2 Antikörper

Bindungsspezifität: N-Term

Sequenz: AERKKRLSII GPTSRDRSSP PPGYIPDELH QVARNGSFTS INSEGEFIPE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 80%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MAP3K2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAP3K2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 619 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MAP3K2

Target: MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))

Andere Bezeichnung: MAP3K2

Hintergrund: MAP3K2 is a component of a protein kinase signal transduction cascade. It regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7. It also plays a role in caveolae kiss-and-run dynamics.The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-18 AF111105.1 37-54 19-79 AI760702.1 474-534 80-371 AF111105.1 116-407 372-2650 AB208963.1 313-2591 2651-3557 AK075004.1 2050-2956 3558-3571 BQ423724.1 71-84 3572-3577 W07290.1 11-16 3578-4302 AK074577.1 1-725 4303-4421 BM470563.1 21-139 4422-4424 AK074577.1 845-847 4425-4941 BM470563.1 142-658
Alias Symbols: MEKK2, MEKK2B
Protein Interaction Partner: MAP3K2, STAMBP, USP2, UBC, MAP2K7, MAP2K5, MAPK7, MAP3K3, XIAP, BIRC2, YWHAB, YWHAE, HSP90AA1, STK38, MAP2K4, MAP2K3, SMURF1, NEDD4, NEDD4L, Stub1, YWHAG, PIBF1, IKBKG, WNK1, SH2D2A, PKN2, MAP3K5, YWHAZ, MAPK8, NFKBIA, SFN,
Protein Size: 619

Molekulargewicht: 70 kDa

Gen-ID: 10746

NCBI Accession: NM_006609, NP_006600

UniProt: Q9Y2U5

Pathways: MAPK Signalweg