SHMT1 Antikörper (N-Term)

Produktnummer ABIN2783618

Der Kaninchen Polyklonal anti-SHMT1 Antikörper (ABIN2783618) detektiert spezifisch SHMT1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Meerschweinchen, Zebrafisch (Danio rerio), Schaf, Kaninchen, Rind (Kuh), Pferd und Saccharomyces cerevisiae.

Kurzübersicht für SHMT1 Antikörper (N-Term) (ABIN2783618)

Target: SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Zebrafisch (Danio rerio), Schaf, Kaninchen, Rind (Kuh), Pferd, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SHMT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SHMT1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: SHMT1 Antibody - N-terminal region

Sequenz: NIIKKESNRQ RVGLELIASE NFASRAVLEA LGSCLNNKYS EGYPGQRYYG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SHMT1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SHMT1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49040-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SHMT1

Target: SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))

Andere Bezeichnung: SHMT1

Hintergrund:

Background Information: This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.

Gene Name: Serine hydroxymethyltransferase 1 (soluble)

Alternative Symbols: SHMT, CSHMT

Protein Name: Serine hydroxymethyltransferase, cytosolic

Molekulargewicht: 53kDa

Gen-ID: 6470

NCBI Accession: NP_004160

UniProt: Q5RFK5