MAP4K2 Antikörper (N-Term)

Produktnummer ABIN2783443

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MAP4K2 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio), Hund, Pferd, Schwein und Kaninchen.

Kurzübersicht für MAP4K2 Antikörper (N-Term) (ABIN2783443)

Target: MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio), Hund, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP4K2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAP4K2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: MAP4K2 Antibody - N-terminal region

Sequenz: HLHPMRALML MSKSSFQPPK LRDKTRWTQN FHHFLKLALT KNPKKRPTAE

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 85%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against MAP4K2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAP4K2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48632-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu MAP4K2

Target: MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))

Andere Bezeichnung: MAP4K2

Hintergrund:

Background Information: MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.

Gene Name: Mitogen-activated protein kinase kinase kinase kinase 2

Alternative Symbols: GCK, BL44, RAB8IP

Protein Name: Mitogen-activated protein kinase kinase kinase kinase 2

Molekulargewicht: 91kDa

Gen-ID: 5871

NCBI Accession: NP_004570

UniProt: Q12851