NEK2 Antikörper (N-Term)
Kurzübersicht für NEK2 Antikörper (N-Term) (ABIN2783428)
Target
Alle NEK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- RCQKIRRKSD GKILVWKELD YGSMTEAEKQ MLVSEVNLLR ELKHPNIVRY
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Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against NEK2. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human NEK2
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 445 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NEK2 (NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2))
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Andere Bezeichnung
- NEK2
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Hintergrund
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This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene.
Alias Symbols: HsPK21, NEK2A, NLK1
Protein Interaction Partner: ANAPC4, UBC, NEK2, CEP250, CTNNB1, PPP1CC, VCP, CDH1, CDC20, CHEK1, CSN2, CDC27, MYC, PPP1CA, CCDC85A, SPTBN4, GIT1, EDRF1, TCF25, IMMT, NDC80, IFT140, PDE4DIP, TPM3, MCC, EIF4A2, DCTN1, CHGA, Gm9174, Cdc16, Cdc23, NEK11, MAD1L1, PPP1R2, MAPK1, CLEC4C,
Protein Size: 445 -
Molekulargewicht
- 52 kDa
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Gen-ID
- 4751
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NCBI Accession
- NM_002497, NP_002488
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UniProt
- P51955
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Pathways
- M Phase
Target
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