GSTM5 Antikörper (N-Term)

Produktnummer ABIN2783390

Produktdetails anti-GSTM5 Antikörper

Target: GSTM5 (Glutathione S-Transferase mu 5 (GSTM5))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSTM5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MPMTLGYWDI RGLAHAIRLL LEYTDSSYVE KKYTLGDAPD YDRSQWLNEK

Homologie: Cow: 93%, Dog: 93%, Goat: 93%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 85%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against GSTM5. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GSTM5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 218 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GSTM5

Target: GSTM5 (Glutathione S-Transferase mu 5 (GSTM5))

Andere Bezeichnung: GSTM5 (GSTM5 Produkte)

Hintergrund: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds.
Alias Symbols: GSTM5-5, GTM5
Protein Interaction Partner: AMOTL2, GSTM5, GSTM3, UBC, PPP1CC,
Protein Size: 218

Molekulargewicht: 26 kDa

Gen-ID: 2949

NCBI Accession: NM_000851, NP_000842

UniProt: P46439