Sep 15 Antikörper (Middle Region)

Produktnummer ABIN2783300

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Sep 15 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Schwein, Zebrafisch (Danio rerio) und Rind (Kuh).

Kurzübersicht für Sep 15 Antikörper (Middle Region) (ABIN2783300)

Target: Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))

Reaktivität: Human, Maus, Ratte, Schwein, Zebrafisch (Danio rerio), Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Sep 15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Sep 15 Antikörper

Bindungsspezifität: Middle Region

Sequenz: SDKPKLFRGL QIKYVRGSDP VLKLLDDNGN IAEELSILKW NTDSVEEFLS

Homologie: Cow: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SEP15. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SEP15

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 165 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Sep 15

Target: Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))

Andere Bezeichnung: SEP15

Hintergrund: SEP15 is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. The gene that encodes the protein is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. This gene is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: -
Protein Interaction Partner: METTL23, UBC, DCUN1D1, CUL3, BAMBI, XRCC6, UGGT2, UGGT1,
Protein Size: 165

Molekulargewicht: 15 kDa

Gen-ID: 9403

NCBI Accession: NM_004261, NP_004252

UniProt: O60613