Decorin Antikörper (N-Term)

Produktnummer ABIN2783275

Produktdetails anti-Decorin Antikörper

Target: Decorin (DCN)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Schwein, Kaninchen, Ziege, Pferd, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Decorin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: IGPEVPDDRD FEPSLGPVCP FRCQCHLRVV QCSDLGLDKV PKDLPPDTTL

Homologie: Cow: 92%, Dog: 100%, Goat: 92%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 86%, Sheep: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against DCN. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DCN

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 359 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Decorin

Target: Decorin (DCN)

Andere Bezeichnung: DCN (DCN Produkte)

Synonyme: CSCD antikoerper, DSPG2 antikoerper, PG40 antikoerper, PGII antikoerper, PGS2 antikoerper, SLRR1B antikoerper, DC antikoerper, mDcn antikoerper, cscd antikoerper, dspg2 antikoerper, pg40 antikoerper, pgii antikoerper, pgs2 antikoerper, slrr1b antikoerper, decorin antikoerper, decorin L homeolog antikoerper, DCN antikoerper, Dcn antikoerper, dcn.L antikoerper, dcn antikoerper

Hintergrund: DCN is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. This protein and biglycan are thought to be the result of a gene duplication. DCN is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.
Alias Symbols: CSCD, DSPG2, PG40, PGII, PGS2, SLRR1B
Protein Interaction Partner: BRCA1, MET, WISP1, COL4A6, COL4A5, FLNA, TNF, TGFB1, THBS1, MMP3, MMP7, SFTPD, PLA2G2A, AHSG, FN1, FBN1, EGFR, ELN, DPT, C1QA, MMP2, COL14A1, COL5A1, COL1A2, COL1A1, COL4A4, COL4A1, COL4A3, TGFB2, COL6A1,
Protein Size: 359

Molekulargewicht: 36 kDa

Gen-ID: 1634

NCBI Accession: NM_001920, NP_001911

UniProt: P07585

Pathways: Glycosaminoglycan Metabolic Process