CRYAB Antikörper (C-Term)

Produktnummer ABIN2783274

Der Kaninchen Polyklonal Anti-CRYAB-Antikörper wurde für WB validiert. Er ist geeignet, CRYAB in Proben von Human, Ratte, Maus, Rind (Kuh), Schaf, Hund, Meerschweinchen, Kaninchen und Pferd zu detektieren.

Kurzübersicht für CRYAB Antikörper (C-Term) (ABIN2783274)

Target: CRYAB (Crystallin, alpha B (CRYAB))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Schaf, Hund, Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRYAB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CRYAB Antikörper

Bindungsspezifität: C-Term

Sequenz: KYRIPADVDP LTITSSLSSD GVLTVNGPRK QVSGPERTIP ITREEKPAVT

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against CRYAB. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CRYAB

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 175 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CRYAB

Target: CRYAB (Crystallin, alpha B (CRYAB))

Andere Bezeichnung: CRYAB

Hintergrund: Alpha crystallins are composed of: alpha-A and alpha-B, for acidic and basic, respectively. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B are differentially expressed, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases, a missense mutation cosegregated in a family with a desmin-related myopathy.
Alias Symbols: CRYA2, CTPP2, HSPB5
Protein Interaction Partner: CRYAB, CRYAA, KRTAP19-5, KRTAP8-1, TRAPPC6A, MRPL11, TNPO2, ACOT7, HSPB1, CASP7, CASP3, CASP2, PIDD1, DDX20, CRADD, B2M, APOC2, XIAP, CASP12, SOD1, HSPB2, HBA1, CASP9, CASP8, CASP6, ASB5, SMAD4, TRIM33, UBC, CCL22, CTNNB1, CRYGD, CDH1, SNCA, GFAP, FGF2, F
Protein Size: 175

Molekulargewicht: 20 kDa

Gen-ID: 1410

NCBI Accession: NM_001885

UniProt: P02511