UMPS Antikörper (C-Term)

Produktnummer ABIN2783243

Dieses Anti-UMPS-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von UMPS in WB und IHC. Geeignet für Human, Maus, Ratte, Kaninchen, Meerschweinchen, Pferd, Hund, Rind (Kuh), Schwein und Saccharomyces cerevisiae. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für UMPS Antikörper (C-Term) (ABIN2783243)

Target: UMPS (Uridine Monophosphate Synthetase (UMPS))

Reaktivität: Human, Maus, Ratte, Kaninchen, Meerschweinchen, Pferd, Hund, Rind (Kuh), Schwein, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UMPS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-UMPS Antikörper

Bindungsspezifität: C-Term

Sequenz: VGFISGSRVS MKPEFLHLTP GVQLEAGGDN LGQQYNSPQE VIGKRGSDII

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%, Yeast: 75%

Produktmerkmale: This is a rabbit polyclonal antibody against UMPS. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human UMPS

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 480 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-UMPS Antikörper (ABIN2783243)

Ishikawa, Kondo, Yamaguchi, Sakamoto, Fujisawa: "Effect of varicocelectomy on patients with unobstructive azoospermia and severe oligospermia." in: BJU international, Vol. 101, Issue 2, pp. 216-8, (2008) (PubMed).

Details zu UMPS

Target: UMPS (Uridine Monophosphate Synthetase (UMPS))

Andere Bezeichnung: UMPS

Hintergrund: OPRT (UMPS) is involved in early events of pancreatic and gallbladder carcinogenesis and invasion of hepatocellular carcinomas. Orotate phosphoribosyltransferase is involved in the invasion and metastasis of colorectal carcinoma. Determination of OPRT levels in gastric carcinoma tissue enables to predict the response to S-1-based neoadjuvant/adjuvant chemotherapy.
Alias Symbols: OPRT
Protein Interaction Partner: UBC, CALU, PLA2G12A, ZNF227, RPS29, PAXIP1, PSEN1, NOS3, APRT, A2M, CUL3, USP50, CDC42EP3, DLST,
Protein Size: 480

Molekulargewicht: 52 kDa

Gen-ID: 7372

NCBI Accession: NM_000373, NP_000364

UniProt: P11172

Pathways: Ribonucleoside Biosynthetic Process