PPP2R5A Antikörper (N-Term)
Kurzübersicht für PPP2R5A Antikörper (N-Term) (ABIN2783198)
Target
Alle PPP2R5A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- YVSTNRGVIV ESAYSDIVKM ISANIFRTLP PSDNPDFDPE EDEPTLEASW
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Homologie
- Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against PPP2R5A. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PPP2R5A
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 486 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PPP2R5A (Protein Phosphatase 2, Regulatory Subunit B' alpha (PPP2R5A))
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Andere Bezeichnung
- PPP2R5A
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Hintergrund
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PPP2R5A belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity.The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: B56A, MGC131915, PR61A
Protein Interaction Partner: ESPL1, PTTG1, UBC, CBX5, Mdm2, Ccng1, PYGM, NEK1, CHEK2, Soga1, Sgol1, Sgol2, Ppp2r1a, AXIN1, MYC, GNL3, TP63, SHC1, CSNK1A1, EIF2AK2, APC, NOS3, MAPT, BEST1, BCL2, JAK2, CTLA4, PPP2R1B, PPP2CA, PPP2R5C,
Protein Size: 486 -
Molekulargewicht
- 56 kDa
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Gen-ID
- 5525
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NCBI Accession
- NM_006243, NP_006234
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UniProt
- Q15172
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Pathways
- PI3K-Akt Signalweg
Target
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