PPP1R13B Antikörper (Middle Region)

Produktnummer ABIN2783179

Der Kaninchen Polyklonal Anti-PPP1R13B-Antikörper wurde für WB validiert. Er ist geeignet, PPP1R13B in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für PPP1R13B Antikörper (Middle Region) (ABIN2783179)

Target: PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP1R13B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PPP1R13B Antikörper

Bindungsspezifität: Middle Region

Sequenz: EFDLVQRIIY EVEDPSKPND EGITPLHNAV CAGHHHIVKF LLDFGVNVNA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PPP1R13B. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PPP1R13B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1090 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PPP1R13B

Target: PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))

Andere Bezeichnung: PPP1R13B

Hintergrund: PPP1R13B is a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.
Alias Symbols: ASPP1, KIAA0771, p53BP2-like, p85
Protein Interaction Partner: TRAF1, CCDC184, MIPOL1, LATS2, SIAH2, PPP1CC, PPP1CA, HRAS, LATS1, KHDRBS1, ERBB2, CEP63, TNIK, CDC5L, UBC, PLEKHA5, APC, TP63, TP73, E2F4, E2F3, E2F2, E2F1,
Protein Size: 1090

Molekulargewicht: 119 kDa

Gen-ID: 23368

NCBI Accession: NM_015316, NP_056131

UniProt: Q96KQ4

Pathways: p53 Signalweg