Frataxin Antikörper (Middle Region)

Produktnummer ABIN785388

Produktdetails anti-Frataxin Antikörper

Target: Frataxin (FXN)

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Pferd, Kaninchen, Rind (Kuh), Meerschweinchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Frataxin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TLDNPSSLDE TAYERLAEET LDSLAEFFED LADKPYTLED YDVSFGDGVL

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against Fxn. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 207 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Frataxin

Target: Frataxin (FXN)

Andere Bezeichnung: Fxn (FXN Produkte)

Synonyme: zgc:158218 antikoerper, LOC100284365 antikoerper, BcDNA:AT09528 antikoerper, CG8971 antikoerper, DFH antikoerper, Dfh antikoerper, Dmel\\CG8971 antikoerper, X25 antikoerper, dfh antikoerper, CyaY antikoerper, FA antikoerper, FARR antikoerper, FRDA antikoerper, RGD1565754 antikoerper, Frda antikoerper, frataxin antikoerper, fxn antikoerper, LOC100284365 antikoerper, TVAG_182150 antikoerper, fh antikoerper, FTX1 antikoerper, FXN antikoerper, Fxn antikoerper

Hintergrund: Fxn promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. It may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. It may be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. It modulates the RNA-binding activity of ACO1.
Alias Symbols: FA, FARR, Frda, X25
Protein Size: 207

Molekulargewicht: 23 kDa

Gen-ID: 14297

NCBI Accession: NM_008044, NP_032070

UniProt: O35943

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size