Frataxin Antikörper (Middle Region)
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- Target Alle Frataxin (FXN) Antikörper anzeigen
- Frataxin (FXN)
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Frataxin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- TLDNPSSLDE TAYERLAEET LDSLAEFFED LADKPYTLED YDVSFGDGVL
- Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against Fxn. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product FXN Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 207 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Frataxin (FXN)
- Andere Bezeichnung
- Fxn (FXN Produkte)
- Hintergrund
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Fxn promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. It may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. It may be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. It modulates the RNA-binding activity of ACO1.
Alias Symbols: FA, FARR, Frda, X25
Protein Size: 207 - Molekulargewicht
- 23 kDa
- Gen-ID
- 14297
- NCBI Accession
- NM_008044, NP_032070
- UniProt
- O35943
- Pathways
- Transition Metal Ion Homeostasis, Regulation of Cell Size
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