PA2G4 Antikörper (Middle Region)
Kurzübersicht für PA2G4 Antikörper (Middle Region) (ABIN2783042)
Target
Alle PA2G4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- PA2G4 Antibody - middle region
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Sequenz
- NCTPIEGMLS HQLKQHVIDG EKTIIQNPTD QQKKDHEKAE FEVHEVYAVD
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 90%, Zebrafish: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against PA2G4. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PA2G4
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108974
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.0 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))
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Andere Bezeichnung
- PA2G4
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Hintergrund
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Background Information: PA2G4 is an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells.
Gene Name: Proliferation-associated 2G4, 38 kDa
Alternative Symbols: EBP1, HG4-1, p38-2G4
Protein Name: Proliferation-associated protein 2G4
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Molekulargewicht
- 44kDa
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Gen-ID
- 5036
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NCBI Accession
- NP_006182
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UniProt
- Q9UQ80
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Pathways
- Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Toll-Like Receptors Cascades
Target
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