AGPAT5 Antikörper (N-Term)

Produktnummer ABIN2782960

Der Kaninchen Polyklonal Anti-AGPAT5-Antikörper wurde für WB validiert. Er ist geeignet, AGPAT5 in Proben von Human, Ratte, Rind (Kuh), Schwein und Saccharomyces cerevisiae zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für AGPAT5 Antikörper (N-Term) (ABIN2782960)

Target: AGPAT5 (1-Acylglycerol-3-Phosphate O-Acyltransferase 5 (Lysophosphatidic Acid Acyltransferase, Epsilon) (AGPAT5))

Reaktivität: Human, Ratte, Rind (Kuh), Schwein, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AGPAT5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-AGPAT5 Antikörper

Bindungsspezifität: N-Term

Sequenz: RLLSAFLPAR FYQALDDRLY CVYQSMVLFF FENYTGVQIL LYGDLPKNKE

Homologie: Cow: 86%, Human: 100%, Pig: 86%, Rat: 79%, Yeast: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against AGPAT5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AGPAT5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 364 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-AGPAT5 Antikörper (ABIN2782960)

Agarwal, Barnes, Garg: "Functional characterization of human 1-acylglycerol-3-phosphate acyltransferase isoform 8: cloning, tissue distribution, gene structure, and enzymatic activity." in: Archives of biochemistry and biophysics, Vol. 449, Issue 1-2, pp. 64-76, (2006) (PubMed).

Details zu AGPAT5

Target: AGPAT5 (1-Acylglycerol-3-Phosphate O-Acyltransferase 5 (Lysophosphatidic Acid Acyltransferase, Epsilon) (AGPAT5))

Andere Bezeichnung: AGPAT5

Hintergrund: Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80 % homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis.
Alias Symbols: 1-AGPAT5, LPAAT-e, LPAAT-epsilon, LPAATE, 1AGPAT5
Protein Interaction Partner: UBQLN1, UBC, ELAVL1, SUMO1,
Protein Size: 364

Molekulargewicht: 42 kDa

Gen-ID: 55326

NCBI Accession: NM_018361, NP_060831

UniProt: Q9NUQ2