Anoctamin 10 Antikörper (C-Term)

Produktnummer ABIN2782940

Es sind 4+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-Anoctamin 10 Antikörper wird verwendet zum Nachweis von Anoctamin 10 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für Anoctamin 10 Antikörper (C-Term) (ABIN2782940)

Target: Anoctamin 10 (ANO10)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Anoctamin 10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Anoctamin 10 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: TMEM16K Antibody - C-terminal region

Sequenz: LKADIDATLY EQVILEKEMG TYLGTFDDYL ELFLQFGYVS LFSCVYPLAA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against TMEM16K. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TMEM16K

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47389-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Anoctamin 10 Antikörper (ABIN2782940)

Wanitchakool, Ousingsawat, Sirianant, Cabrita, Faria, Schreiber, Kunzelmann: "Cellular defects by deletion of ANO10 are due to deregulated local calcium signaling." in: Cellular signalling, Vol. 30, pp. 41-49, (2016) (PubMed).

Schreiber, Kunzelmann: "Expression of anoctamins in retinal pigment epithelium (RPE)." in: Pflügers Archiv : European journal of physiology, Vol. 468, Issue 11-12, pp. 1921-1929, (2016) (PubMed).

Hammer, Wanitchakool, Sirianant, Papiol, Monnheimer, Faria, Ousingsawat, Schramek, Schmitt, Margos, Michel, Kraiczy, Pawlita, Schreiber, Schulz, Fingerle, Tumani, Ehrenreich, Kunzelmann: "A Coding Variant of ANO10, Affecting Volume Regulation of Macrophages, Is Associated with Borrelia Seropositivity." in: Molecular medicine (Cambridge, Mass.), Vol. 21, pp. 26-37, (2015) (PubMed).

Tian, Schreiber, Kunzelmann: "Anoctamins are a family of Ca2+-activated Cl- channels." in: Journal of cell science, Vol. 125, Issue Pt 21, pp. 4991-8, (2013) (PubMed).

Details zu Anoctamin 10

Target: Anoctamin 10 (ANO10)

Andere Bezeichnung: TMEM16K

Hintergrund:

Background Information: TMEM16K is a multi-pass membrane protein. It belongs to the anoctamin family. TMEM16K may act as a calcium-activated chloride channel.

Gene Name: Anoctamin 10

Alternative Symbols: SCAR10, TMEM16K

Protein Name: Anoctamin-10

Molekulargewicht: 76kDa

Gen-ID: 55129

NCBI Accession: NP_060545

UniProt: Q9NW15