COQ2 Antikörper (Middle Region)

Produktnummer ABIN2782857

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-COQ2 Antikörper (ABIN2782857) detektiert spezifisch COQ2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Schwein, Hund, Ziege, Pferd, Kaninchen, Saccharomyces cerevisiae und Zebrafisch (Danio rerio).

Kurzübersicht für COQ2 Antikörper (Middle Region) (ABIN2782857)

Target: COQ2 (Coenzyme Q2 Homolog, Prenyltransferase (COQ2))

Reaktivität: Human, Maus, Ratte, Schwein, Hund, Ziege, Pferd, Kaninchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COQ2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-COQ2 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: COQ2 Antibody - middle region

Sequenz: FSGVMWTLIY DTIYAHQDKR DDVLIGLKST ALRFGENTKP WLSGFSVAML

Homologie: Dog: 93%, Goat: 79%, Horse: 79%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 93%, Rat: 86%, Yeast: 91%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against COQ2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human COQ2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47180-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-COQ2 Antikörper (ABIN2782857)

Sasaki, Kotoh, Watadani, Matsumoto: "New animal models reveal that coenzyme Q2 (Coq2) and placenta-specific 8 (Plac8) are candidate genes for the onset of type 2 diabetes associated with obesity in rats." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 26, Issue 11-12, pp. 619-29, (2015) (PubMed).

Details zu COQ2

Target: COQ2 (Coenzyme Q2 Homolog, Prenyltransferase (COQ2))

Andere Bezeichnung: COQ2

Hintergrund:

Background Information: COQ2 catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. COQ2 mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB.CoQ (ubiquinone) serves as a redox carrier in the mitochondrial respiratory chain and is a lipid-soluble antioxidant. COQ2, or parahydroxybenzoate-polyprenyltransferase (EC 2.5.1.39), catalyzes one of the final reactions in the biosynthesis of CoQ, the prenylation of parahydroxybenzoate with an all-trans polyprenyl group (Forsgren et al., 2004 [PubMed 15153069]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-90 BC020728.1 1-90 91-96 BG699931.1 80-85 97-789 BC020728.1 97-789 790-792 BQ363759.1 169-171 793-1535 BC020728.1 793-1535 1536-1554 BC008804.2 1496-1514

Gene Name: Coenzyme Q2 homolog, prenyltransferase (yeast)

Alternative Symbols: MSA1, CL640, COQ10D1, PHB:PPT

Protein Name: 4-hydroxybenzoate polyprenyltransferase, mitochondrial

Molekulargewicht: 42kDa

Gen-ID: 27235

NCBI Accession: NP_056512

UniProt: Q96H96