BMP10 Antikörper (C-Term)

Produktnummer ABIN2782814

Der Kaninchen Polyklonal Anti-BMP10-Antikörper wurde für WB validiert. Er ist geeignet, BMP10 in Proben von Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd und Meerschweinchen zu detektieren.

Kurzübersicht für BMP10 Antikörper (C-Term) (ABIN2782814)

Target: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMP10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BMP10 Antikörper

Bindungsspezifität: C-Term

Sequenz: GYEAYECRGV CNYPLAEHLT PTKHAIIQAL VHLKNSQKAS KACCVPTKLE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against BMP10. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human BMP10

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu BMP10

Target: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Andere Bezeichnung: BMP10

Hintergrund: BMP10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. It acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth.
Alias Symbols: -
Protein Interaction Partner: BMPR2, ACVR2B, ACVR2A, SERINC3,
Protein Size: 424

Molekulargewicht: 46 kDa

Gen-ID: 27302

NCBI Accession: NM_014482, NP_055297

UniProt: O95393

Pathways: Hormone Activity, Regulation of Muscle Cell Differentiation