DGCR2 Antikörper (Middle Region)

Produktnummer ABIN2782668

Der Kaninchen Polyklonal anti-DGCR2 Antikörper (ABIN2782668) detektiert spezifisch DGCR2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Hund, Pferd, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für DGCR2 Antikörper (Middle Region) (ABIN2782668)

Target: DGCR2 (DGS2) (DiGeorge Syndrome Chromosome Region-2 (DGS2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Hund, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DGCR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DGCR2 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: DGCR2 Antibody - middle region

Sequenz: AESCYEKSSF LCKRSQTCVD IKDNVVDEGF YFTPKGDDPC LSCTCHGGEP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against DGCR2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DGCR2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46576-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu DGCR2

Target: DGCR2 (DGS2) (DiGeorge Syndrome Chromosome Region-2 (DGS2))

Andere Bezeichnung: DGCR2

Hintergrund:

Background Information: Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Alternative splicing results in multiple transcript variants.

Gene Name: DiGeorge syndrome critical region gene 2

Alternative Symbols: IDD, LAN, DGS-C, SEZ-12

Protein Name: integral membrane protein DGCR2/IDD

Molekulargewicht: 61kDa

Gen-ID: 9993

NCBI Accession: NP_005128

UniProt: P98153