DGCR2 Antikörper (Middle Region)

Produktnummer ABIN2782668

Produktdetails anti-DGCR2 Antikörper

Target: DGCR2 (DGS2) (DiGeorge Syndrome Chromosome Region-2 (DGS2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Hund, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DGCR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AESCYEKSSF LCKRSQTCVD IKDNVVDEGF YFTPKGDDPC LSCTCHGGEP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against DGCR2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DGCR2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 550 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DGCR2

Target: DGCR2 (DGS2) (DiGeorge Syndrome Chromosome Region-2 (DGS2))

Andere Bezeichnung: DGCR2 (DGS2 Produkte)

Synonyme: DGS-C antikoerper, IDD antikoerper, LAN antikoerper, SEZ-12 antikoerper, CIDD antikoerper, 9930034O06Rik antikoerper, Dgsc antikoerper, Idd antikoerper, Lan antikoerper, Sez12 antikoerper, mKIAA0163 antikoerper, zgc:91974 antikoerper, DiGeorge syndrome critical region gene 2 antikoerper, DiGeorge syndrome critical region gene 2 S homeolog antikoerper, DGCR2 antikoerper, Dgcr2 antikoerper, dgcr2 antikoerper, dgcr2.S antikoerper

Hintergrund: Deletions of the 22q11.2 have been associated with a wide range of developmental defects classified under the acronym CATCH 22. The DGCR2 is a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome.
Alias Symbols: DGS-C, DKFZp686I1730, IDD, KIAA0163, LAN, SEZ-12
Protein Interaction Partner: HNRNPD, SMURF2, DDIT3,
Protein Size: 550

Molekulargewicht: 61 kDa

Gen-ID: 9993

NCBI Accession: NM_005137, NP_005128

UniProt: P98153