IL11RA Antikörper (N-Term)

Produktnummer ABIN2782643

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch IL11RA in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Hund.

Kurzübersicht für IL11RA Antikörper (N-Term) (ABIN2782643)

Target: IL11RA (Interleukin 11 Receptor, alpha (IL11RA))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL11RA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IL11RA Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: IL11RA Antibody - N-terminal region

Sequenz: QLGYPPARPV VSCQAADYEN FSCTWSPSQI SGLPTRYLTS YRKKTVLGAD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against IL11RA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IL11RA

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46466-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu IL11RA

Target: IL11RA (Interleukin 11 Receptor, alpha (IL11RA))

Andere Bezeichnung: IL11RA

Hintergrund:

Targeted Subunit: alpha

Background Information: Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. IL11RA is the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain.Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Alternative splicing has been observed at this locus and two variants, each encoding a distinct isoform, have been identified.

Gene Name: Interleukin 11 receptor, alpha

Alternative Symbols: CRSDA

Protein Name: Interleukin-11 receptor subunit alpha

Molekulargewicht: 45 kDa

Gen-ID: 3590

NCBI Accession: NP_004503

UniProt: Q14626

Pathways: JAK-STAT Signalweg, Growth Factor Binding