IL11RA Antikörper (N-Term)

Produktnummer ABIN2782643

Produktdetails anti-IL11RA Antikörper

Target: IL11RA (Interleukin 11 Receptor, alpha (IL11RA))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL11RA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QLGYPPARPV VSCQAADYEN FSCTWSPSQI SGLPTRYLTS YRKKTVLGAD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against IL11RA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IL11RA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 422 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IL11RA

Target: IL11RA (Interleukin 11 Receptor, alpha (IL11RA))

Andere Bezeichnung: IL11RA (IL11RA Produkte)

Synonyme: CRSDA antikoerper, fi26e06 antikoerper, il-11ra antikoerper, wu:fi26e06 antikoerper, AI314697 antikoerper, GP130 antikoerper, Il-11ra antikoerper, Il11ra antikoerper, Il11ra2 antikoerper, NR1 antikoerper, interleukin 11 receptor subunit alpha antikoerper, interleukin 11 receptor, alpha antikoerper, interleukin 11 receptor subunit alpha 1 antikoerper, interleukin 11 receptor, alpha chain 1 antikoerper, IL11RA antikoerper, il11ra antikoerper, Il11ra1 antikoerper, Il11ra antikoerper

Hintergrund: Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. IL11RA is the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain.Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Alternative splicing has been observed at this locus and two variants, each encoding a distinct isoform, have been identified.
Alias Symbols: MGC2146, CRSDA
Protein Interaction Partner: IL11,
Protein Size: 422

Molekulargewicht: 43 kDa

Gen-ID: 3590

NCBI Accession: NM_004512, NP_004503

UniProt: Q14626

Pathways: JAK-STAT Signalweg, Growth Factor Binding